Abstract Library

#913 A PCR-Based Multigene Transcript Analysis Blood Test Outperforms Chromogranin A in the Detection of Gastrointestinal and Pancreatic Neuroendocrine Tumors and is Unaffected by PPI Use or Hypertension

Introduction: A critical requirement in the management of gut NETs is a blood biomarker test that is sensitive, specific and reproducible.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Modlin I

Authors: Modlin I, Kidd M, Drozdov I, Aslanian H, Alaimo D,

Keywords: biomarker, CgA, NET, PCR,

#344 Cell Cycle Phase Expression Profile Guided Selection of Proliferative Markers for Well-differentiated Small Intestinal Neuroendocrine Neoplasms

Introduction: Grading of neuroendocrine lesions is often determined by Ki-67 (immunostain), despite limited prognostic ability for this cell cycle marker in well-differentiated tumors (WDNETs) and carcinomas.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Lawrence B, Kidd M, Alaimo D, Svejda B, Drozdov I,

Keywords: biomarker, Ki-67, NALP1, neuroendocrine tumor, PCR, proliferation, survivin, transcript,

#312 Evidence for the role of miR196a in regulating small intestinal neuroendocrine tumor proliferation and metastasis via HOX/AKT pathway activation

Introduction: MicroRNAs (miRNAs) regulate cell proliferation, differentiation, and apoptosis functioning as tumor suppressor genes but their role in NET proliferation and metastasis has not been fully evaluated.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Kidd M, Lawrence B, Alaimo D, Svejda B, Schimmack S,

Keywords: AKT, carcinoid, HOX, miRNA, metastasis, neuroendocrine tumor, proliferation, small intestine,

#175 The Immunohistochemical (IHC) Expression and Prognostic Value of ER, PR, and HER2/neu in Pancreatic and Small Intestinal Neuroendocrine Tumors

Introduction: There has been limited study of ER and PR expression in gastrointestinal neuroendocrine tumors (GINETs) and data on HER2/neu overexpression in GINETS has been conflicting.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Rayson D, Arnason T, Barnes P, Drewniak M, Abdolell M,

Keywords: progesterone receptor, her2/neu, ginets, tissue microarray,

#174 Loss of Expression of the DNA Mismatch Repair Proteins MLH1 and MSH2 is Rare in Pancreatic and Small Intestinal Neuroendocrine Tumors

Introduction: Loss of expression of the DNA mismatch repair (MMR) proteins MLH1 and MSH2, which is known to correlate strongly with MSI, has not been well studied in pancreatic or small intestinal NETs.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Rayson D, Arnason T, Sapp H, Barnes P, Drewniak M,

Keywords: microsatellite instability, tissue microarray, pnets, small intestinal nets,